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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRF
All Species:
25.76
Human Site:
S253
Identified Species:
40.48
UniProt:
P11831
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11831
NP_003122.1
508
51593
S253
L
T
Y
Q
V
S
E
S
D
S
S
G
E
T
K
Chimpanzee
Pan troglodytes
XP_518487
508
51590
S253
L
T
Y
Q
V
S
E
S
D
S
S
G
E
T
K
Rhesus Macaque
Macaca mulatta
XP_001093365
508
51688
S253
L
T
Y
Q
V
S
E
S
D
S
S
G
E
T
K
Dog
Lupus familis
XP_852302
508
51510
S253
L
T
Y
Q
V
S
E
S
D
S
S
G
E
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM73
504
51229
S249
L
T
Y
Q
V
S
E
S
D
S
S
G
E
T
K
Rat
Rattus norvegicus
NP_001102772
504
51157
S249
L
T
Y
Q
V
S
E
S
D
S
S
G
E
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517936
150
15822
Chicken
Gallus gallus
Q90718
375
39146
T133
T
K
D
V
L
K
P
T
F
T
V
T
N
L
P
Frog
Xenopus laevis
P23790
448
46097
S206
T
D
L
T
Y
Q
V
S
E
S
D
S
S
G
E
Zebra Danio
Brachydanio rerio
NP_001103996
539
55032
M241
G
L
T
E
P
K
E
M
L
K
P
T
F
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24535
449
47603
Q206
L
S
T
L
T
G
T
Q
V
M
L
L
V
A
S
Honey Bee
Apis mellifera
XP_001120126
351
36852
E108
C
V
P
D
N
L
E
E
S
F
T
S
L
G
Q
Nematode Worm
Caenorhab. elegans
NP_492296
327
35027
T85
E
L
S
T
L
T
G
T
Q
V
M
L
L
V
A
Sea Urchin
Strong. purpuratus
XP_796790
410
43027
H168
I
P
S
D
S
Q
H
H
S
R
N
P
D
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11746
286
32783
M44
S
K
R
K
H
G
I
M
K
K
A
F
E
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
97.2
N.A.
96.4
96.6
N.A.
22.8
66.5
72.4
57.7
N.A.
35
33.4
28.7
33.8
Protein Similarity:
100
99.8
98.8
98
N.A.
97.4
97.6
N.A.
24
69.6
76.9
67.7
N.A.
48.8
40.3
41.1
45.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
0
13.3
13.3
N.A.
6.6
6.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
20
26.6
20
N.A.
13.3
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
14
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
14
0
0
0
0
40
0
7
0
7
0
0
% D
% Glu:
7
0
0
7
0
0
54
7
7
0
0
0
47
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
7
0
7
7
0
0
% F
% Gly:
7
0
0
0
0
14
7
0
0
0
0
40
0
14
0
% G
% His:
0
0
0
0
7
0
7
7
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
0
14
0
7
0
14
0
0
7
14
0
0
0
0
40
% K
% Leu:
47
14
7
7
14
7
0
0
7
0
7
14
14
14
0
% L
% Met:
0
0
0
0
0
0
0
14
0
7
7
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
7
0
7
0
0
% N
% Pro:
0
7
7
0
7
0
7
0
0
0
7
7
0
0
7
% P
% Gln:
0
0
0
40
0
14
0
7
7
0
0
0
0
7
7
% Q
% Arg:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
7
% R
% Ser:
7
7
14
0
7
40
0
47
14
47
40
14
7
0
14
% S
% Thr:
14
40
14
14
7
7
7
14
0
7
7
14
0
47
0
% T
% Val:
0
7
0
7
40
0
7
0
7
7
7
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
40
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _